Publications

Our Published Work (from the most recent):

Hsu C., Serio A., Amdursky N., Besnard C., Stevens M.M. “Fabrication of Hemin-Doped Serum Albumin-Based Fibrous Scaffolds for Neural Tissue Engineering Applications” ACS Applied Materials & Interfaces (2017) – Manuscript accepted

Serio A., et al. “Heterospectral lipidomics for biomolecular profiling of remyelination in multiple sclerosis ” ACS Central Science (2017) – published on-line DOI: 10.1021/acscentsci.7b00367

Serio A. & Patani R. ““Resolving Cellular    Autonomy in Human Neurodegeneration” (Review) Stem Cells (2017) – Manuscript accepted DOI: 10.1002/stem.2758

Hall, C. E., Yao Z., Choi M., Tyzak G., Serio A., et al. Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS. Cell Rep 19, 1739–1749 (2017).

Bell K., Al-Mubarak B., et al. “Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2” Nature Communications (2015) Vol.6 March

Fuhrmann G., Serio A., Mazo M., Nair R., Stevens M.M. “Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins” Journal of Controlled Release (2014) 205: 35-44.

Barmada, S.J., Serio, A., et al. “Neuronal autophagy induction enhances TDP43 turnover and survival in rodent and human models of ALS” Nature Chemical Biology (2014) 10 (8), pp. 677-685.

Horejs, C.-M., Serio, A., et al. “Biologically-active laminin-111 fragment that modulates the epithelial-to-mesenchymal transition in embryonic stem cells” Proc Natl Acad Sci USA (2014): 111 (16), pp. 5908-5913

Pedroni, S.M.A., et al. “Complement inhibition and statins prevent fetal brain cortical abnormalities in a mouse model of preterm birth” Biochimica et Biophysica Acta-Molecular Basis of Disease (2014) 1842(1): 107 – 115

Serio, A., et al. “Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy” Proc Natl Acad Sci USA (2013) 110(12): 4697 – 4702

Bilican, B., Serio, A., et.al. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability” Proc Natl Acad Sci USA (2012) 109(15): 5803 – 5808

Bilican, B., Serio, A., et.al. “Unpicking neurodegeneration in a dish with human pluripotent stem cells: One cell type at a time” Cell Cycle (2013) 12(15): 2339 – 2340

Hampton D.W., Serio A., et al. “Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis” Acta neuropathologica communications (2013) 1 (1), p. 84.

Bilican, B., Serio, A., et.al. Comment on “Drug screening for ALS using patient-specific induced pluripotent stem cells” Science Translational Medicine (2013) 5(188): 188le2

Gupta K., Patani R., Baxter P., Serio A., et al. Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms” Cell Death and Differentiation (2012) 19(5): 779 – 787

Ruzov A., Tsenkina Y., Serio A., et al. Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development” Cell Research (2011) 21(9): 1332 – 1342

Serio A., Chandran S.   “The use of stem cells in motor neurone disease (MND)” Advances in Clinical Neuroscience & Rehabilitation (2011) 11(5): 10 11