Our Published Work (from the most recent):
Hagemann, C. et al. Combining SLA 3D printing and soft lithography for fast, versatile, and accessible high-resolution fabrication of customised multiscale cell culture devices with complex designs. Biorxiv 2022.02.22.481424 (2022) doi:10.1101/2022.02.22.481424.
Hagemann, C. et al. Axonal Length Determines Distinct Homeostatic Phenotypes in Human iPSC Derived Motor Neurons on a Bioengineered Platform. Adv Healthc Mater 2101817 (2022) doi:10.1002/adhm.202101817.
Harley, J., Hagemann, C., Serio, A. & Patani, R. TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain. Brain Commun 3, fcab166 (2021).
Bennett, A. et al. Comparative Structural, Biophysical, and Receptor Binding Study of True Type and Wild type AAV2. J Struct Biol 107795 (2021) doi:10.1016/j.jsb.2021.107795.
Hagemann, C. et al. Automated and unbiased discrimination of ALS from control tissue at single cell resolution. Brain Pathology Zurich Switz 31, e12937 (2021).
Iglesias-Rey, S. et al. Unsupervised Cell Segmentation and Labelling in Neural Tissue Images. Appl Sci 11, 3733 (2021).
Harley, J., Hagemann, C., Serio, A. & Patani, R. FUS is lost from nuclei and gained in neurites of motor neurons in a human stem cell model of VCP-related ALS. Brain 143, awaa339 (2020).
Ritzau‐Reid, K. I. et al. An Electroactive Oligo‐EDOT Platform for Neural Tissue Engineering. Adv Funct Mater 30, 2003710 (2020).
Weskamp, K. et al. Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS. J Clin Invest 130, 1139–1155 (2020).
Bergholt, M. S., Serio, A. & Albro, M. B. Raman Spectroscopy: Guiding Light for the Extracellular Matrix. Frontiers Bioeng Biotechnology 7, 303 (2019).
Secchi, V. et al. Biofunctionalization of TiOinf2/inf Surfaces with Self-Assembling Layers of Oligopeptides Covalently Grafted to Chitosan. Acs Biomater Sci Eng 5, (2019).
Gopal, S. et al. Immunogold FIB-SEM: Combining Volumetric Ultrastructure Visualization with 3D Biomolecular Analysis to Dissect Cell–Environment Interactions. Adv Mater 31, (2019).
Serio, A. & Patani, R. Concise Review: The Cellular Conspiracy of Amyotrophic Lateral Sclerosis. Stem Cells 36, (2018).
Hsu, C.-C., Serio, A., Amdursky, N., Besnard, C. & Stevens, M. M. Fabrication of Hemin-Doped Serum Albumin-Based Fibrous Scaffolds for Neural Tissue Engineering Applications. Acs Appl Mater Inter 10, (2018).
Bergholt, M. S. et al. Correlated heterospectral lipidomics for biomolecular profiling of remyelination in multiple sclerosis. Acs Central Sci 4, (2018).
Armstrong, J. P. K. et al. Engineering Anisotropic Muscle Tissue using Acoustic Cell Patterning. Adv Mater 30, (2018).
Hall, C. E. et al. Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS. Cell Reports 19, 1739–1749 (2017).