Welcome to the group website of the Serio Lab!
We are the Neural Circuit BioEngineering Group, within the Division of Tissue Engineering & Biophotonics at King's College London. We combine bioengineering, stem cell biology, neuroscience and molecular imaging to recreate the complexity of the nervous system in vitro.
We firmly believe that in order to really understand something, it is certainly necessary to take it apart, study and understand every piece and then... to put it back together!
We stand on the shoulders of giants: for over 30 years neurobiology, genetics, cell and developmental biology have worked together to provide an understanding of which cells, molecules and genes are necessary to construct the nervous system. And in parallel, the emergence of stem cell technologies and bioengineering techniques has given us the tools to interact with biological material in a productive way.
Our aim is to combine these fields into a dedicate research avenue, gaining an understanding of how the nervous system works in health and disease by trying to construct bespoke complex circuitry in vitro. Engineering connections between neural cells in a meaningful way, to advance our knowledge and push towards translational outcomes.